2019 - 2020

0351-3203
  Physical Organic Chemistry  
FACULTY OF EXACT SCIENCES | SCHOOL OF CHEMISTRY
Prof. Vigalok ArkadiOrnstein - Chemistry110 Mon1200-1400 Sem  2
 
 
University credit hours:  2.0

Course description
  • Thermodynamics and kinetics of organic reactions. Methods to study mechanisms of organic reactions. Kinetic isotope effect. Linear free energy relationships (Hammett, Brown, Tafts, etc.)
  • Solvent effect on chemical reactivity. Solvation properties and scales. Equation of Grunwald & Weinstein, Z-factor, ET(30). Polar aprotic solvents and their influence on chemical reactivity. Phase-transfer catalysis. Hydrophobic effects
  • Reactive intermediates- carboanions. pKa of C-H acids. Stability and reactivity of carboanions. NMR characterization and ion-pairing of simple organometallic derivatives
  • Reactive intermediates- carbocations. Generation and stability of carbocations. Rearrangements involving carbocations. Classic and non-classic carbocations

accessibility declaration


tel aviv university